For all their problems this season Manchester United should be able to beat Young Boys on Tuesday and, if Juventus get the better of Valencia, seal their place in the last 16 of the Champions League.
Young Boys are 16 points clear of second-placed Basel in the Swiss Super League after defeating Lugano 1-0 on Saturday.
However, they have found the step up in class to the Champions League almost impossible to breach and have only picked up one point from their first four Group H matches.
It may not be pretty at Old Trafford, where United have scored only eight goals in six Premier League fixtures this season, but Jose Mourinho’s can edge to a narrow victory against the Swiss outfit.
Elsewhere, Juventus can get back on track following their shock home loss to United by beating a Valencia team that find goals hard to come by – they have scored only 11 in 13 La Liga games – while in Group G CSKA Moscow can keep their slim hopes of qualifying for the last 16 alive by beating Viktoria Plzen by a one-goal margin (23/10).
Real Madrid have been shocking of late but they can usually be relied on to come up with the goods in Europe and can draw against a Roma side that have struggled themselves recently.
Roma lost 1-0 at Udinese on Saturday and are seventh in Serie A, and a draw on Tuesday would suit them as well as Real.
In Group F, Manchester City should exact revenge for their surprising home loss to Lyon in September by beating the French side 2-0 (37/4) – a result which would enhance Hoffenheim’s chances of progressing.
The Bundesliga outfit have not won any of their four group matches to date but should edge to victory against Shakhtar Donetsk.
Bayern Munich and Ajax are in pole position to qualify from Group E and they can both win on Tuesday.
Bayern, who have won the trophy five times, may well beat Benfica from behind at 11/2 while four-time winners Ajax should get the better of AEK Athens in Greece.
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