Barcelona saw their unbeaten run come to an end last week against neighbours Espanyol and will be out for revenge in the second leg.
Los Periquitos had waited nine years for that victory but lost 3-0 to Sevilla at the weekend and will now be expecting a backlash.
Barca smashed Real Betis 5-0 and will be plotting more of the same.
In fact, they have netted four or more in their last five competitive matches at home against their neighbours and will be baying for blood.
Expect a big home win but with that result so short, look for the goals market.
Lionel Messi saw a penalty saved last week and Barcelona are 33/10 to score from the spot this time around.
It could be a riot at the Nou Camp and taking into account all of the above, the home side to win by four goals or more is my bet at 31/20.
Elsewhere and I am also thinking about Strasbourg to beat Lille in the Coupe de France.
Le Racing have enjoyed a sterling return to the top flight, currently sitting 10th, and will see this as a bit of a free hit.
Although Christophe Galtier seems to be slowly gaining control of his pack of Dogues, who were stray under Marcelo Bielsa, he will not mind sacrificing the Coupe.
The Alsatians won 3-0 when the pair met at the Stade de la Meinau and I think 13/10 for another home triumph is too good to miss.
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